And lastly, clonidine enhances neuraxial opioids and, in combination with fentanyl, interacts in an additive way, which could lessen the dose of each part by 60% for postoperative analgesia.Clonidine is dispersed in breast milk; caution is encouraged if lactating. Consult with with all your medical doctorDue to impact of clonidine around the sympat
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